Process for the preparation of L-amino acids using

专利名称：Process for the preparation of L-amino acids

using a gene encoding 6-phosphogluconatedehydrogenase

发明人：L. K. Duncan,Ashling McCormack,Cliona

Stapleton,Kevin Burke,Bettina Mockel

申请号：US10686736申请日：20031017

公开号：US20040063181A1公开日：20040401

专利附图：

摘要：The invention relates to a process for the preparation of L-amino acids. The

process involves fermenting an L-amino acid producing coryneform bacteria in a culturemedium, concentrating L-amino acid produced by the fermenting in the culture mediumor in the cells of the bacteria, and isolating the L-amino acid produced. The bacteria hasan overexpressed gene encoding 6-phosphogluconate dehydrogenase and a decreasedor switched off gene encoding pyruvate oxidase. The L-amino acid may be L-lysine, L-threonine, L-isoleucine or L-tryptophan. `

申请人：DEGUSSA-HULS AKTIENGASELLSCHAFT,NATIONAL UNIVERSITY OF IRELAND

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