第四届有机合成与药物研发国际研讨会

第四届有机合成与药物研发国际研讨会（The 4th International Symposium on Organic Synthesis and Drug Discovery ）将于5月24-25日在我校举行，会议报告日程如下：

Saturday Morning (May 24th) Lecture hall in Jiangsu Normal University Time 7:30 Opening Remarks 8:00-8:15 Chair Lecturer Get on the bus from the hotel to Jiangsu Normal University Guigen Li, Shu-Jiang Tu Ping Ren (President, Jiangsu Normal University) Yi Pan (Vice President for Research, Nanjing University) Robert Huber (Nobel Laureate, Max-Planck-Institut fuer Biochemie) K1: Structural Biology and its Translation into Practice and Business, my Experience Photo Taken and Coffee Break Plenary Lectures Victor Hruby (University of Arizona) P1: Design and Synthesis of Multivalent Ligands for the Detection and Treatment of Disease Zhu-Jun Yao (Nanjing University) P2: Total Synthesis of Azaphilonoids and Development of Bioactive Mimetics Shu-Li You (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences) P3: Transition-Metal-Catalyzed Asymmetric Allylic Dearomatization Reactions Thomas J. Colacot (Johnson Matthey Catalysis & Chiral Technologies) P4: Understanding Cu Free Sonogashira Coupling Keynote Lecture 8:15-9:00 9:00-9:20 Chen-Ho Tung 9:20-10:00 Guigen Li 10:00-10:40 10:40-11:20 Chengjian Zhu 11:20-12:00 12:00-14:30

Go back to the hotel by bus for lunch at “All Day Dining” and poster Saturday Afternoon (May 24th) Pearl and Agate Room (2nd floor) in Hotel Section 1. Drug Design and Biomed Science Time Chair Lecturer Hong Yan (Nanjing University) A1: Variable photophysical properties of phosphorescent iridium (III) complexes triggered by closo- or nido-carborane substitution Dieter Cremer Elfi Kraka (Southern Methodist University) A2: What Can We Learn From Nature? Research Connecting The In Vivo With The In Silico World Raghu Kannan A3: Translational cancer nanomedicine: current status and future opportunities Coffee Break Section 4. Organic and Material Synthesis Dieter Cremer (Southern Methodist University) A4: Investigation of Protein Structure with Quantum Chemical Methods: Hydrogen-bonding and Protein Similarity Jie Wu 16:35-17:00 Yan Zhang (Nanjing University) A5: Reactions of photo-active molecules and their biological applications Amber Room (2nd floor) in Hotel Section 2. Organic and Material Synthesis Chair Lecturer Chengjian Zhu (Nanjing University) B1: Sustainable Functionalization of Innate sp3 C-H Bonds and the Construction of Heterocyclic Compounds 14:30-14:55 14:55-15:20 Hans Adolfsson Jie Wu (Fudan University) B2: Insertion of sulfur dioxide: Synthesis of aryl N-aminosulfonamides Xuefeng Jiang (East China Normal University) B3: Sulfur Atom Transfer (SAT) Reaction and Synthesis of Sulfur-Containing Drugs and Natural Products 15:20-15:45 15:45-16:00 Section 3. Drug Design and Biomedical Sciences 16:00-16:35 Hans Adolfsson (Stockholm University) B4: Catalytic synthesis with, and of, amines and amides 17:00-17:25 18:00-20:00 Shaowu Wang (Anhui Normal Shu-Li You University) B5: Lewis Acid Catalyzed [3+3] Annulation Strategy for Synthesis of Heterocyclic Compounds Feng Shi (Jiangsu Normal Jonathan Baell (Monash University) University) B6: Stereoselective Synthesis of A6: Approaches to Discover Nitrogenous Heterocycles Based on Anticancer Agents that Target Orangocatalytic Asymmetric Bcl-XL Reactions Banquet at Crowne International Ballroom III Sunday Morning (May 25th) Pearl and Agate Room (2nd floor) in Hotel Amber Room (2nd floor) in Hotel Section 5. Organic and Process Synthesis Section 6. Synthetic Methodology Time Chair Lecturer Joseph Sclafani (Teva Branded Pharmaceutical R & D) A7: An Improved Synthesis of Obatoclax Mesylate Chair Lecturer Steve Han (Boehringer Ingelheim Pharmaceutical) B7: Efficient Enantioselective Synthesis of Complex Drug Substances on Large Scale Hongjian Lu (Nanjing University) B8: Stereoselective Radical C–H Amination via Co(II)-Based Metalloradical Catalysis Lei Yu (Yangzhou University) B9: Organoselenium Catalysis in Pharmacal Intermediate Synthesis 8:30-9:05 Elfi Kraka 9:05-9:30 9:30-9:55 Wanbin Zhang 9:55-10:20 10:20-10:35 10:35-11:00 10:00-11:25 Joseph Sclafani Wanbin Zhang (Shanghai Jiao Tong University) A8: Novel Axially Chiral Ligands and Catalysts for Efficient Asymmetric Catalysis Qing Xu (Wenzhou University) A9: The Development of Alcohol-Based Dehydrative Alkylation Methods and Related Reactions Yaping Yan Li (Zhongnan Hospital of Hong Wuhan University) A10: Development of Peptide Doxorubicin (PDOX) as a Molecular Targeting Drug to Treat Cancer Metastasis Coffee Break Xingwang Wang (Soochow University) A11: Asymmetric Organocatalysis for Enantioselective Construction of Multistereogenic Annulations Chao-Guo Yan (Yangzhou University) A12: Synthesis of polycyclic dispirooxindoles via Tao three-component reactions of Jiang 4-cycanopyridine, electron-deficient alkynes and isatins Dingjun Wang (Canan Material Inc.) A13: Applications of Precious Metal Catalysts in Pharmaceutical and Fine Chemical Industries Hua Wang Hua Wang (Henan University) B10: The Construction of Thiophene-based Helices Xu Cheng (Nanjing University) B11: The Asymmetric Synthesis of Chiral carboniolamide Shouyun Yu (Nanjing University) B12: Synthesis of (Hetero)Arenes Using Visble Light-Promoted Somophilic Triple Bond Insertions Wen-Hua Zheng (Nanjing University) B13: Desymmetrization of 2-substituted 1,3-diol via Brønsted acid mediated oxidative cleavage of benzylidene acetal 11:25-11:50 12:00-13:30 Lunch at “All Day Dining” and poster

Sunday afternoon (May 25th) Plenary Lectures: Crowne International Ballroom I (1st floor) in Hotel Time 13:30-14:10 Shaowu Wang 14:10-14:50 Chair Lecturer Zhenfeng Xi (Peking University) P5: Synthesis of Semibullvalenes and Diazasemibullvalenes via Organo-di-Metallic Reagents Yian Shi (Colorado State University) P6: Catalytic Stereoselective C-X Bond Formation Andrei Yudin (University of Toronto) P7: New approaches in synthetic methods using amphoteric molecules Zhenfeng Xi 15:30-16:10 16:10-16:20 Closing Remarks

László Kürti (UT Southwestern Medical Center) P8: New Methods for the Rapid Synthesis of Biaryl Ligands and N-Heterocycles Shu-Jiang Tu, Guigen Li 14:50-15:30