专利名称:Method of treatment of cardiovascular
injuries
发明人:Karen S. Moulton,Judah Folkman申请号:US09822765申请日:20010330
公开号:US20020006895A1公开日:20020117
摘要:The present invention provides a method for treating cardiovascular ailments.The method involves first screening an individual to determine their risk of having thepotential for unstable plaques. Such individuals can be selected by looking at one of thefollowing criteria: (i) increased plaque neovascularization, (ii) area ratio of intima to wallarea of a plaque, (iii) evidence of plaque hemorrhage, or (iv) inflammatory cells associatedwith plaque vessels. Looking at these criteria permits one to select individuals having thepotential for unstable plaques. The method then involves treating the selected individualwith an effective amount of an angiogenesis inhibitor.
申请人:CHILDREN'S MEDICAL CENTER CORPORATION
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