专利名称：Methods for the treatment of disorders of
the cardiac vascular system
发明人：Marvin B. Bacaner申请号：US07/403128申请日：19890905公开号：US05036106A公开日：19910730
摘要：Methods are described to utilize synergistic interactions by variouscombinations of (1) bethanidine and various tricyclic compounds, (2) bethanidine andbretylium tosylate, (3) bretylium tosylate and various tricyclic compounds, and (4)debrisoquin sulfate and various tricyclic compounds, preferably in a single injectable ororal dosage form, to prevent, treat, and reduce the vulnerability of the heart toventricular fibrillation and other ventricular arrhythmias in animals, both human andotherwise. Also, the use of bethanidine and bretylium tosylate in combination, and theuse of debrisoquin sulfate for the resuscitation of pulseless beings, the use ofdebrisoquin sulfate for the suppression of ventricular fibrillation and ventricular
tachycardia, and the use of bethanidine as an antidote to tricyclic antidepressant toxicityare disclosed.
申请人：BACANER; MARVIN B.
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