专利名称：USE OF THERAPEUTICALLY EFFECTIVE
LIPIDS AND METHOD FOR PRODUCINGORGAN-/TISSUE-SPECIFIC
THERAPEUTICALLY EFFECTIVE LIPIDS
发明人：Wolfgang STREMMEL申请号：US14520001申请日：20141021
公开号：US20150038472A1公开日：20150205
摘要：The use of therapeutically active lipids for organ/tissue-specific enrichment forthe treatment of inflammatory, ischemic or degenerative disorders and/or for stimulatinga regeneration is arranged and developed such that the lipids are bound on applicationto carrier molecules for which cell-specific uptake systems in the cells of the organsand/or tissue exist. In addition, a method of producing organ/tissue-specific
therapeutically active lipids for treatment of inflammatory, ischemic or degenerativedisorders and/or stimulation of a regeneration, in particular for treating inflammatoryliver disorders, is claimed, which is arranged and developed such thatlysophosphatidylethanolamine (LysoPE) is coupled to the carboxyl group of
ursodeoxycholate (UrsoDOCA) converted to an ester to give a LysoPE-DOCA compound.
申请人：PAT GmbH
地址：Munchen DE
国籍：DE
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